Yoshihiro Yonekawa, MD
RETINA Roundup Editor in Chief
2025 was a successful year for RETINA and Retinal Cases and Brief Reports, with numerous high impact papers published by authors from throughout the world.
We have compiled the top 10 accessed papers in 2025 below, with direct links to the articles. Age-related macular degeneration and imaging continue to be hot topics, and we also see articles on inherited retinal degenerations, surgical studies, and ocular oncology.
We hope you enjoy our most popular papers of the year:
1. Retinal Optical Coherence Tomography Imaging Biomarkers. A Review of the Literature
Pandya, Bhadra U.; Grinton, Michael; Mandelcorn, Efrem D.; Felfeli, Tina
2. LIGHTSITE III: 13-Month Efficacy and Safety Evaluation of Multiwavelength Photobiomodulation in Nonexudative (Dry) Age-Related Macular Degeneration Using the Lumithera Valeda Light Delivery System
Boyer, David; Hu, Allen; Warrow, David; Xavier, Samantha; Gonzalez, Victor; Lad, Eleonora; Rosen, Richard B.; Do, Diana; Schneiderman, Todd; Ho, Allen; Munk, Marion R.; Jaffe, Glenn; Tedford, Stephanie E.; Croissant, Cindy L.; Walker, Michael; Rückert, Rene; Tedford, Clark
3. Suprachoroidal Space Injection Technique: Expert Panel Guidance
Wykoff, Charles C.; Avery, Robert L.; Barakat, Mark R.; Boyer, David S.; Brown, David M. MD; Brucker, Alexander J.; Cunningham, Emmett T. Jr.; Heier, Jeffrey S.; Holekamp, Nancy M.; Kaiser, Peter K.; Khanani, Arshad M. MD, MA; Kim, Judy E.; Demirci, Hakan; Regillo, Carl D.; Yiu, Glenn C.; Ciulla, Thomas A.
4. Comparison of Three Internal Limiting Membrane Peeling Techniques for Myopic Traction Maculopathy with High Risk of Postoperative Macular Hole Development
Feng, Jingyang; Shao, Qing; Xie, Jiaming; Yu, Jiayi; Li, Menghan; Liu, Chen; Zhou, Siheng; Zhou, Hao; Wang, Weijun; Fan, Ying
5. Pigment Epithelial Detachment Thickness and Variability Affects Visual Outcomes in Patients with Neovascular Age-Related Macular Degeneration
Sarraf, David; Khanani, Arshad M.; Sadda, SriniVas R.; Chang, Andrew; Wong, David T.; Kempf, Anne-Sophie; Saffar, Insaf; Tang, Shuhan; Tadayoni, Ramin
6. A Systematic Literature Review of Disease Progression Reported in RPGR-associated X-Linked Retinitis Pigmentosa
Lam, Byron L.; Scholl, Hendrik P. N.; Doub, Daneal; Sperling, Marvin; Hashim, Mahmoud; Li, Nan
7. The Pathophysiology of Geographic Atrophy Secondary to Age-Related Macular Degeneration and the Complement Pathway as a Therapeutic Target
Boyer, David S.; Schmidt-Erfurth, Ursula; van Lookeren Campagne, Menno; Henry, Erin C.; Brittain, Christopher
8. Choroidal Nevus Imaging Features in 3,806 Cases and Risk Factors for Transformation into Melanoma in 2,355 Cases
Shields, Carol L.; Dalvin, Lauren A.; Ancona-Lezama, David; Yu, Michael D.; Di Nicola, Maura; Williams, Basil K. Jr; Lucio-Alvarez, J. Antonio; Ang, Su Mae; Maloney, Sean; Welch, R. Joel; Shields, Jerry A
9. Optimal Management of Pigment Epithelial Detachments in Eyes with Neovascular Age-Related Macular Degeneration
Khanani, Arshad M.; Eichenbaum, David; Schlottmann, Patricio G.; Tuomi, Lisa; Sarraf, David
10. Retinal fluid and thickness as measures of disease activity in neovascular age-related macular degeneration
Kaiser, Peter K.; Wykoff, Charles C.; Singh, Rishi P.; Khanani, Arshad M.; Do, Diana V.; Patel, Hersh; Patel, Nikhil
